李亚平

一、个人简介

   李亚平，讲师，硕士生导师。2016年博士毕业于香港城市大学。近年来主持河北省自然科学基金青年科学基金项目1项、河北大学高层次人才启动项目1项，河北大学医学学科培育项目1项。

   联系方式：E-mail: liyaping@hbu.edu.cn            

二、主讲课程及研究方向 

   1.主讲课程：卫生毒理学

   2.研究方向：肿瘤的发展、转移及细胞耐药性研究；微流控芯片开发用于细胞生物学研究。

三、代表性论文

1. Lina Zheng, Keying Li, Xianmei Tang, Cuiping Li, Hailiang Nie, Lirong Han*, Yaping Li*. A microfluidic co-culture platform for lung cancer cells electrotaxis study under the existence of stromal cells. Bioelectrochemistry. 2025, 164: 108917.

2. Cuiping Li*, Mengfan Pang, Yaping Li*, Lirong Han, Yajiao Fan, Xuelian Xin, Xian Zhang, Ning Zhang, Yan Qin. Protective effect of vitamin C against tetrachlorobenzoquinone-induced 5-hydroxymethylation-dependent apoptosis in HepG2 cells mainly via the mitochondrial apoptosis pathway. Ecotoxicology and Environmental Safety. 2023, 260: 115097.

3. Yaping Li, Xiao Pan; Mingyuan Yin, Cuiping Li, Lirong Han*. Preventive effect of lycopene in dextran sulfate sodium-induced ulcerative colitis mice through the regulation of TLR4/TRIF/NF-κB signaling pathway and tight junctions. Journal of Agricultural and Food Chemistry. 2021, 69(45): 13500-13509.

4. Dandan Liu, Yingcai Hong, Yaping Li, Chong Hu, Tak-Chun Yip, Wai-Kin Yu, Yu Zhu, Chi-Chun Fong, Weimao Wang, Siu-Kie Au, Shubin Wang, Mengsu Yang*. Targeted destruction of cancer stem cells using multifunctional magnetic nanoparticles that enable combined hyperthermia and chemotherapy. Theranostics. 2020, 10: 1181.

5. Tao Xu, Huayang Fu, Yaping Li, Xiaomei Chen, Wah Cheuk, Cheuk Wing Li, Heng Zou, Wanqing Yue, Siu Kei Au, Yuan Wang, Mengsu Yang*. Single cell target gene mutation analysis by arc-edge-channel monolithic valve microfluidic cell isolation and locked nucleic acid-based PCR detection. Sensors and Actuators B: Chemical. 2019, 293: 224-234.

6. Yaping Li, Wai-Kin Yu, Likun Chen, Yuen-san Chan, Dandan Liu, Chi-Chun Fong, Tao Xu, Guangyu Zhu, Dong Sun, Mengsu Yang*. Electrotaxis of tumor-initiating cells of H1975 lung adenocarcinoma cells is associated with both activation of stretch-activated cation channels (SACCs) and internal calcium release. Bioelectrochemistry. 2018, 124: 80-92.

四、科研项目

    1.河北省自然科学基金青年项目，项目号：B2020201008, 2020.01-2022.12，主持。

    2.河北大学医学学科培育项目，项目号：2020B23, 2020.07-2023.06，主持。