李亚平

一、个人简介

        李亚平，讲师，硕士生导师。2016年博士毕业于香港城市大学。近年来主持河北省自然科学基金青年科学基金项目1项、河北大学高层次人才启动项目1项，河北大学医学学科培育项目1项。

        联系方式：E-mail: liyaping@hbu.edu.cn           

二、主讲课程及研究方向

1.主讲课程：卫生毒理学实验

2.研究方向：肿瘤的发展、转移及细胞耐药性研究；微流控芯片开发用于细胞生物学研究。

三、代表性论文

1. Yaping Li, Xiao Pan; Mingyuan Yin, Cuiping Li, Lirong Han. Preventive Effect of Lycopene in Dextran Sulfate Sodium-Induced Ulcerative Colitis Mice through the Regulation of TLR4/TRIF/NF-κB Signaling Pathway and Tight Junctions, Journal of Agricultural and Food Chemistry, 2021, 69(45): 13500-13509.

2. Xu, Tao; Fu, Huayang; Li, Yaping; Chen, Xiaomei; Cheuk, Wah; Li, Cheuk Wing; Zou, Heng; Yue, Wanqing; Au, Siu Kei; Wang, Yuan; Yang, Mengsu ; Single cell target gene mutation analysis by arc-edge-channel monolithic valve microfluidic cell isolation and locked nucleic acid-based PCR detection, Sensors and Actuators B: Chemical, 2019, 293: 224-234.

3. Yaping Li, Wai-Kin Yu, Likun Chen, Yuen-san Chan, Dandan Liu, Chi-Chun Fong, Tao Xu, Guangyu Zhu, Dong Sun, Mengsu Yang. Electrotaxis of tumor-initiating cells of H1975 lung adenocarcinoma cells is associated with both activation of stretch-activated cation channels (SACCs) and internal calcium release. Bioelectrochemistry, 2018, 124, 80-92.

4. Yaping Li, Tao Xu, Heng Zou, Xiaomei Chen, Dong Sun, Mengsu Yang. Cell migration microfluidics for electrotaxis-based heterogeneity study of lung cancer cells.  Biosensors and Bioelectronics, 2017, 89, 837-845.

5. Yaping Li, Tao Xu, Xiaomei Chen, Shin Lin, Michael Cho, Dong Sun, Mengsu Yang. Effects of direct current electric fields on lung cancer cell electrotaxis in a PMMA-based microfluidic device. Analytical and Bioanalytical Chemistry, 2017, 409, 2163-2178.

四、科研项目

1.河北省自然科学基金青年项目，项目号：B2020201008, 2020.01-2022.12，主持。

2.河北大学医学学科培育项目，项目号：2020B23, 2020.07-2023.06，主持。